Cannabidiol (CBD) is a type of cannabinoid, a naturally occurring chemical compound found in cannabis plants. CBD is often sold as an oil, and it can be taken orally, inhaled as a vapor, or applied topically.
CBD is available in many forms including gummies, pills, creams, and oils. It’s also possible to get CBD in beauty products like shampoo, soap, and lotions.
CBD has been touted for several health benefits including relief from anxiety and pain. But there is also some concern that it could interact with other medications you take. cbd gummies for sleep reviews help to know about CBD drug interactions.
CBD and Medications That Are Broken Down by the Liver
There are three main ways that CBD can interact with other medications. The first has to do with how CBD is metabolized by your body.
CBD is broken down by enzymes in your liver. These enzymes are responsible for breaking down many of the medications you take.
The liver enzymes that break down CBD are also responsible for breaking down some medications used to treat epilepsy and seizures. These include clobazam (Onfi), diazepam (Valium), and zonisamide (Zonegran).
Taking CBD along with these medications might decrease the effects of these medications. If you take one of these medications, you might need a higher dose to feel the same effects. This could increase your risk of side effects from these medications.
You should avoid taking CBD if you’re taking any of these medications:
- Clobazam (Onfi)
- Diazepam (Valium)
- Zonisamide (Zonegran)
CBD and Medications That Are Metabolized by the Garcinia Cambogia Fruit
The garcinia cambogia fruit contains a chemical called hydroxycitric acid (HCA). HCA is responsible for breaking down many different medications.
Taking CBD along with HCA might decrease the effects of HCA. If you take HCA, you might need a higher dose to feel the same effects. This could increase your risk of side effects from HCA.
Some of the medicines that are broken down by HCA include:
- Acetaminophen
- Amlodipine
- aspirin
- Atorvastatin
- Celecoxib
- Diclofenac
- Esomeprazole
- Lansoprazole
- Losartan
- Naproxen
- Omeprazole
Medications that CBD can increase the effects of:
CBD is a potent inhibitor of cytochrome P450 (CYP450), an enzyme responsible for metabolizing many drugs. When CBD is taken with medication that is metabolized by CYP450, it can result in higher-than-expected levels of the medication in your system. This could cause increased side effects or make the medication less effective. Some common medications that are metabolized by CYP450 include:
- Blood pressure medications (beta blockers)
- Antihistamines
- Prokinetics
- HMG CoA reductase inhibitors (statins)
- Calcium channel blockers
- Benzodiazepines
- Antidepressants
Conclusion
Cannabidiol (CBD) is a type of cannabinoid, a naturally occurring chemical compound found in cannabis plants. It’s thought to have many therapeutic benefits, such as relieving pain and anxiety. However, it can also interact with certain medications. Therefore, it’s important to talk to your doctor before taking CBD if you’re taking any medication that’s metabolized by the liver or garcinia cambogia fruit. Doing so will help ensure that you don’t experience any adverse drug interactions.
